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Mouse Monoclonal Antibody to ABCC4
Description |
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. |
References |
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1. Biochem Pharmacol. 2012 Aug 1;84(3):366-73. 2. Arch Dermatol Res. 2012 Jan;304(1):57-63. |
Specification | |
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Aliases | MRP4; MOATB; MOAT-B; EST170205 |
Entrez GeneID | 10257 |
Swissprot | O15439 |
clone | 2D2A9 |
WB Predicted band size | 150kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human ABCC4 (AA: 631-692) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application | |
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IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Flow cytometric analysis of A549 cells using ABCC4 mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using ABCC4 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using ABCC4 mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30521
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