Description
MGMT involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated

References
Folia Neuropathol. 2013;51(4):275-82. Fam Cancer. 2013 Sep;12(3):449-58.

Specification
Entrez GeneID	4255
Swissprot	P16455
clone	1A11A8
WB Predicted band size	21.6kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human MGMT (AA: 32-210) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
ELISA	1/10000