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Mouse Monoclonal Antibody to CD354
Description |
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This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
References |
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1.Mol Oral Microbiol. 2017 Aug;32(4):275-287. 2.Immunol Lett. 2016 Mar;171:50-9. |
Specification | |
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Aliases | TREM1; TREM-1 |
Entrez GeneID | 54210 |
Swissprot | Q9NP99 |
clone | 6B12D1 |
WB Predicted band size | 26.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat,Monkey |
Immunogen | Purified recombinant fragment of human CD354 (AA: extra 21-205) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application | |
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using CD354 mouse mAb against HepG2 (1), COS7 (2), A549 (3), SPC-A-1 (4), and C6 (5) cell lysate.
- Flow cytometric analysis of HL-60 cells using CD354 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31537
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