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Mouse Monoclonal Antibody to IFNGR1
Description |
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This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. |
References |
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1.Cell Mol Gastroenterol Hepatol. 2021;12(2):465-487. 2.J Clin Immunol. 2021 May;41(4):834-836. |
Specification | |
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Aliases | CD119; IFNGR; IMD27A; IMD27B |
Entrez GeneID | 3459 |
Swissprot | P15260 |
clone | 3B2D4 |
WB Predicted band size | 54.4kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human IFNGR1 (AA: extra 18-245) expressed in HEK293-6e cells supernatant. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application | |
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ICC | 1/50 - 1/200 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Immunofluorescence analysis of Hela cells using IFNGR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Flow cytometric analysis of Hela cells using IFNGR1 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#32402
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