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Mouse Monoclonal Antibody to CD339
Description |
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The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
References |
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1.Cancer Sci. 2016 Nov;107(11):1705-1716. 2.Gene. 2016 Jan 15;576(1 Pt 3):381-4. |
Specification | |
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Aliases | JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1 |
Entrez GeneID | 182 |
Swissprot | P78504 |
clone | 7C7E1 |
WB Predicted band size | 133.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD339 (AA: extra 47-212) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application | |
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31550
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