Description

Tubulin, beta 3, also known as TUBB3. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, a- and

References
1. Histopathology. 2007 Jun;50(7):949-52. 2. Neurochem Res. 2007 Aug;32(8):1387-98. 3. Exp Eye Res. 1995 Apr;60(4):385-400.

Specification
Aliases	tubulin, beta 3; MC1R; TUBB4
Entrez GeneID	10381
Swissprot	Q13509
clone	2E9
WB Predicted band size	50~55kDa
Host/Isotype	Mouse IgG1
Antibody Type	Loading Control Antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Purified recombinant fragment of human TUBB3 expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
ICC	1/200 - 1/1000
FCM	1/200 - 1/400
ELISA	1/10000