Androgen receptor[30007]

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Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human Prostate tissues using Androgen receptor mouse mAb

Immunohistochemical analysis of paraffin-embedded human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining.

Mouse Monoclonal Antibody to Androgen receptor

货号：
30007
别名：
NR3C4; KD; AIS; SMAX1; HUMARA; AR
应用：
WB,IHC
反应种属：
Human
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to Androgen receptor

Description
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Description

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

References
1. Chin Med J (Engl). 2009 Nov 20;122(22):2779-83. 2. Taiwan J Obstet Gynecol. 2009 Sep;48(3):262-7. 3. Prostate. 2008 Mar 1;68(4):453-61. 4. Cancer Res. 2007 May 15;67(10):4630-7.

Specification
Aliases	NR3C4; KD; AIS; SMAX1; HUMARA; AR
Entrez GeneID	367
Swissprot	P10275
clone	2H8
WB Predicted band size	110kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human AR expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.