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Mouse Monoclonal Antibody to PRDM1
Description |
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PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. |
References |
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1. Nat Cell Biol. 2006 Jun;8(6):623-30. 2. Int J Hematol. 2007 Dec;86(5):429-37. 3. Nat Genet. 2008 Aug;40(8):955-62. |
Specification | |
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Aliases | BLIMP1; PRDI-BF1; MGC118922; MGC118923; MGC118924; MGC118925; PRDM1 |
Entrez GeneID | 639 |
Swissprot | O75626 |
clone | 5E7 |
WB Predicted band size | 88kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of human PRDM1 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application | |
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30020
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