Description
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

References
1. Mol Cell Endocrinol. 1997 May 16;129(2):199-208. 2. J Immunol. 1999 Dec 15;163(12):6651-8. 3. J Biol Chem. 1999 Oct 29;274(44):31531-42.

Specification
Aliases	JTK10; JAK2
Entrez GeneID	3717
Swissprot	O60674
clone	1C1
WB Predicted band size	130.6kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
WB	1/500 - 1/2000
ELISA	1/10000