HIF2a[90011]

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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using HIF2a mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using HIF2a mouse mAb (green) and negative control (red).

Flow cytometric analysis of HepG2 cells using HIF2a mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human baldder cancer tissues using HIF2a mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human kidney tissues using HIF2a mouse mAb with DAB staining.

Mouse Monoclonal Antibody to HIF2a

货号：
90011
别名：
HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73
应用：
IHC,ICC,FCM
反应种属：
Human
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to HIF2a

Description
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

Description

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

References
1,Nat Commun. 2020 Oct 6;11(1):5023. 2,Blood Cells Mol Dis. 2020 Sep;84:102446.

Specification
Aliases	HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73
Entrez GeneID	2034
Swissprot	Q99814
clone	1H3E12
WB Predicted band size	96.5kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human HIF2a (AA: 680-870) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide