Description

NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

References
1. Stem Cells Dev. 2005 Aug;14(4):425-39. 2. Cancer Res. 2003 Sep 1;63(17):5329-34. 3. Circ J. 2002 Jun;66(6):561-3.

Specification
Aliases	CSX; NKX2E
Entrez GeneID	1482
Swissprot	P52952
clone	2E1
WB Predicted band size	35kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human NKX2.5 expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
ELISA	1/10000