Description

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

References
1. J Hepatol. 2009 Apr;50(4):746-54. 2. Int J Gynecol Pathol. 2009 May;28(3):211-21.

Specification
Aliases	RY; APG-2; hsp70; hsp70RY; HS24/P52; MGC131852; HSPA4
Entrez GeneID	3308
Swissprot	P34932
clone	5A6
WB Predicted band size	70kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human HSP70 expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
IHC	1/200 - 1/1000
ICC	1/200 - 1/1000
ELISA	1/10000