Description
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

References
1. Chronobiol Int. 2007;24(5):783-92. 2. Mol Cell Biol. 2008 Oct;28(19):6056-65. 3. J Affect Disord. 2009 Sep;117(1-2):87-97.

Specification
Aliases	TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515; ARNTL
Entrez GeneID	406
Swissprot	O00327
clone	1C5
WB Predicted band size	68.7kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human ARNTL expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
IHC	1/200 - 1/1000
ELISA	1/10000