LIN28[20271]

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Western blot analysis using LIN28 mouse mAb against NTERA-2 cell lysate (1).

Confocal Immunofluorescence analysis of methanol fixed Hela cells were transfected with pMX construct of human LIN28, cells were analyzed ~62 hours after transfection.

Confocal Immunofluorescence analysis of NTERA-2 cells using LIN28 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal Antibody to LIN28

货号：
20271
别名：
CSDD1; LIN-28; LIN28A; ZCCHC1
应用：
ICC
反应种属：
Human
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to LIN28

Description
LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

Description

LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

References
1. Dev Dyn. 2005 Feb;232(2):487-97. 2. Mol Cell Biol. 2005 Nov;25(21):9198-208.

Specification
Aliases	CSDD1; LIN-28; LIN28A; ZCCHC1
Entrez GeneID	79727
Swissprot	Q9H9Z2
clone	6D1F9
WB Predicted band size	23kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.